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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBX6
All Species:
32.42
Human Site:
S178
Identified Species:
59.44
UniProt:
O95947
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95947
NP_004599.2
436
47045
S178
R
V
Y
I
H
P
D
S
P
A
T
G
A
H
W
Chimpanzee
Pan troglodytes
XP_523337
436
47083
S178
R
V
Y
I
H
P
D
S
P
A
T
G
A
H
W
Rhesus Macaque
Macaca mulatta
XP_001098963
496
53657
S178
R
V
Y
I
H
P
D
S
P
A
T
G
A
H
W
Dog
Lupus familis
XP_547068
436
47185
S178
R
V
Y
I
H
P
D
S
P
A
T
G
A
H
W
Cat
Felis silvestris
Mouse
Mus musculus
P70327
540
58610
S178
R
V
Y
I
H
P
D
S
P
A
T
G
A
H
W
Rat
Rattus norvegicus
Q5I2P1
517
57726
A279
P
F
S
S
E
T
R
A
L
S
T
S
S
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520749
277
31432
P53
H
G
F
R
L
R
C
P
G
L
F
N
L
L
N
Chicken
Gallus gallus
P79779
361
41167
T137
K
L
K
L
T
N
N
T
L
D
Q
H
G
H
I
Frog
Xenopus laevis
Q8AV66
506
56540
S183
R
V
Y
I
H
P
D
S
P
A
P
G
S
H
W
Zebra Danio
Brachydanio rerio
P79742
473
53459
P177
D
P
C
T
P
H
N
P
G
A
Y
L
R
F
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24432
972
102538
S415
R
M
Y
I
H
P
D
S
P
T
T
G
E
Q
W
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19691
423
46979
Y186
I
L
N
S
M
H
K
Y
Q
P
R
L
H
V
V
Sea Urchin
Strong. purpuratus
XP_797010
645
70075
S224
R
L
Y
I
H
P
D
S
P
A
T
G
A
V
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
81.8
90.1
N.A.
64.4
34.8
N.A.
43.8
35
43
37
N.A.
22.8
N.A.
35.5
30.2
Protein Similarity:
100
99
83.2
92.1
N.A.
67.9
48.5
N.A.
48.3
47.4
54.5
52.8
N.A.
30.7
N.A.
52.5
43.8
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
0
6.6
86.6
6.6
N.A.
73.3
N.A.
0
86.6
P-Site Similarity:
100
100
100
100
N.A.
100
33.3
N.A.
6.6
40
93.3
13.3
N.A.
80
N.A.
6.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
62
0
0
47
0
0
% A
% Cys:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
62
0
0
8
0
0
0
0
0
% D
% Glu:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% E
% Phe:
0
8
8
0
0
0
0
0
0
0
8
0
0
8
0
% F
% Gly:
0
8
0
0
0
0
0
0
16
0
0
62
8
0
0
% G
% His:
8
0
0
0
62
16
0
0
0
0
0
8
8
54
0
% H
% Ile:
8
0
0
62
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
8
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% K
% Leu:
0
24
0
8
8
0
0
0
16
8
0
16
8
8
8
% L
% Met:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
8
16
0
0
0
0
8
0
8
8
% N
% Pro:
8
8
0
0
8
62
0
16
62
8
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
8
0
0
8
0
% Q
% Arg:
62
0
0
8
0
8
8
0
0
0
8
0
8
0
0
% R
% Ser:
0
0
8
16
0
0
0
62
0
8
0
8
16
0
0
% S
% Thr:
0
0
0
8
8
8
0
8
0
8
62
0
0
0
8
% T
% Val:
0
47
0
0
0
0
0
0
0
0
0
0
0
16
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
62
% W
% Tyr:
0
0
62
0
0
0
0
8
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _